Production and storage of synthetic mRNA can introduce a variety of byproducts which reduce the overall integrity and functionality of mRNA vaccines and therapeutics. mRNA integrity is therefore desig
Green is RNA FISH using a probe against XIST RNA. Red is an anti-macroH2A antibody. Blue is DAPI. These images were used to calculate data shown in Table 2.
We present Barcoded Oligonucleotides Ligated On RNA Amplified for Multiplexed and parallel In Situ analyses (BOLORAMIS), a reverse transcription-free method for spatially-resolved, targeted, in situ R