Mmp12

ENCODES a protein that exhibits calcium ion binding (ortholog); collagen binding (ortholog); core promoter sequence-specific DNA binding (ortholog); INVOLVED IN positive regulation of epithelial cell proliferation; regulation of trophoblast cell migration; response to hypoxia; ASSOCIATED WITH abnormal uterine spiral artery remodeling; decreased fetal weight; decreased litter size; ASSOCIATED WITH anti-basement membrane glomerulonephritis; Cerebral Hemorrhage; crescentic glomerulonephritis; FOUND IN cytoplasm (ortholog); extracellular space (ortholog); nucleus (ortholog); INTERACTS WITH (R)-lipoic acid; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol

编码一种展现钙离子结合（同源）；胶原蛋白结合（同源）；核心启动子序列特异性DNA结合（同源）的蛋白质；参与上皮细胞增殖的正向调控；滋养层细胞迁移的调控；对缺氧的反应；与异常子宫螺旋动脉重塑、胎儿体重减轻、胎仔数量减少相关；与抗基底膜肾小球肾炎、脑出血、新月体肾小球肾炎相关；存在于细胞质（同源）、细胞外空间（同源）、细胞核（同源）中；与（R）-α-硫辛酸、1,2-二甲基肼、17α-乙炔基雌二醇相互作用。