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Rh(III)-Catalyzed Selective Coupling of <i>N</i>‑Methoxy‑1<i>H</i>‑indole-1-carboxamides and Aryl Boronic Acids

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A Rh­(III)-catalyzed selective coupling of N-methoxy-1H-indole-1-carboxamide and aryl boronic acids is reported. The coupling is mild and efficient toward diverse product formation, with selective C–C and C–C/C–N bond formation. Kinetic isotope effects studies were conducted to reveal a mechanism of C–H activation and electrophilic addition.

创建时间:
2014-07-03
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