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Adaptation of the Kinome Promotes Resistance to BET Bromodomain Inhibitors in Ovarian Cancer

ChEBI2016-07-21 更新2026-07-12 收录

卵巢癌耐药性

激酶组适应性

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-82329 数据链接链接失效反馈

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资源简介：

Adaptation of the Kinome Promotes Resistance to BET Bromodomain Inhibitors in Ovarian Cancer

应用场景：

创建时间：

2016-07-21

卵巢癌耐药性

miRNA表达谱分析

Cisplatin-resistance is a major cause of treatment failure in human ovarian cancer. Besides lots of genes involved, emerging evidences demonstrate that miRNAs contribute to cisplatin-resistance in can

NIAID Data Ecosystem90

FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy [ID8 and ID8-IP / KMF cells]

卵巢癌耐药性

FAK靶向治疗

Gene copy number changes, cancer stem cell (CSC) increases, and platinum chemotherapy resistance contribute to poor prognosis in patients with recurrent high grade serous ovarian cancer (HGSOC). CSC p

NIAID Data Ecosystem70

MicroRNA profiling in resistance ovarian cell lines. MicroRNA profiling in resistance ovarian cell lines

卵巢癌耐药性

miRNA表达谱

Although many genes associated with the development of resistance to chemotherapy are known, the mechanisms of their regulation are still poorly understood. One of the ways to regulate gene expression

NIAID Data Ecosystem50

Cisplatin Resistant Spheroids Model Clinically Relevant Survival Mechanisms in Ovarian Tumors

卵巢癌耐药性

基因表达特征分析

The majority of ovarian tumors eventually recur in a drug resistant form. Using cisplatin sensitive and resistant cell lines assembled into 3D spheroids we profiled gene expression and identified cand

NIAID Data Ecosystem90

Additional file 8 of Identification and validation of genes associated with prognosis of cisplatin-resistant ovarian cancer

卵巢癌耐药性

癌症预后生物标志物

Supplementary Material 8.

Figshare2024-08-18 更新50