Mesenchymal stem cells overexpressing neuropeptide S promote the recovery of rats with spinal cord injury by activating the PI3K/AKT/GSK3ß signaling pathway

Overexpressing EMSCs can significantly improve the therapeutic effect of spinal cord injury in rats, which provides strong support for the feasibility of the use of gene modification of mesenchymal stem cells in clinical applications. Overall design: Total RNA was extracted from EMSCs and NPS-EMSC by TRIzol Reagent, in duplicate3.