Crystal structure of human FPPS in complex with WC01088

Crystal structure of human FPPS in complex with WC01088 Descriptor: (2-{2-[(2S)-3-methylbutan-2-yl]-5-phenyl-1H-indol-3-yl}ethane-1,1-diyl)bis(phosphonic acid), Farnesyl pyrophosphate synthase, GLYCEROL, ... Authors: Park, J, Zielinski, M, Weiling, C, Tsantrizos, Y.S, Berghuis, A.M. Deposit date: 2014-07-21 Release date: 2015-02-25 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase. Bioorg.Med.Chem.Lett., 25, 2015人源法尼基焦磷酸合酶（Farnesyl pyrophosphate synthase, FPPS）与WC01088复合物的晶体结构 描述符：(2-{2-[(2S)-3-甲基丁-2-基]-5-苯基-1H-吲哚-3-基}乙烷-1,1-二基)双膦酸、法尼基焦磷酸合酶、甘油（GLYCEROL）等 作者：Park J、Zielinski M、Weiling C、Tsantrizos Y.S、Berghuis A.M 沉积日期：2014-07-21 发布日期：2015-02-25 最后修改日期：2023-09-20 检测方法：X射线衍射（1.9 Å） 引用文献：《探究结合于人源法尼基焦磷酸合酶活性位点与变构口袋的配体分子与结构特征》，发表于《Bioorg.Med.Chem.Lett.》2015年第25卷