Histone_marks_controlling_IAP_retrotransposons_activity
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https://www.ncbi.nlm.nih.gov/sra/ERP009246
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资源简介：
We will associate H3K9me3 enrichment with IAP methylation and transcritpion changes in ES cells. IAPs are normally kept methylated in ES cells and only in Dnmt1 knock out ES cells this class of transposons is being demethylated (Arand et al., PLoS Genet, 8(6), June 2012). The same demethylation is happening in 2i conditions (Seisenberger et al., Molecular Cell, 48(6):849{862, December 2012). Dnmt1 conditional knockdown ES cells will be used for studying H3K9me3 enrichment at different time points of Dnmt1 knockdown (Liu et al., Nat Commun, 4:1563, March 2013).
创建时间：
2021-02-04
