Functional identification of SARS-CoV-2 CD4+ T cell epitopes.

1Screened peptide sequences are named based on the protein they are contained within, followed by the number of the first amino acid residue of the peptide in the context of the full protein to the last amino acid residue. Peptides within the "Spike" peptide library correspond with SARS-CoV Spike due to library availability. 2 Average fold over background IFN-γ+ CD4+T cells stimulated with listed peptides. Background is defined as the frequency of IFN-γ+ CD4+T cells in a well stimulated with vehicle control. The average and standard deviation is from three independent experiments 3Analogous SARS-CoV-2 peptide name in instances where SARS-CoV peptide library had to be used due to reagent availability. 4SARS-CoV-2 peptide sequence in instances where SARS-CoV peptide library was used the analogous SARS-CoV-2 peptide sequence is noted.