Patchy accumulation of apical Na+ transporters allows cross talk between extracellular space and cell nucleus.
收藏PubMed Central1992-01-01 更新2026-05-16 收录
下载链接：
https://pmc.ncbi.nlm.nih.gov/articles/PMC48212/
下载链接
链接失效反馈官方服务：
资源简介：
Intracellular Na+ activities and local current densities were measured in fused Madin-Darby canine kidney cells using Na+ and voltage-sensing microelectrodes. Na+ that enters the cell across the apical plasma membrane accumulates initially in the nucleoplasm, several seconds ahead of its appearance in the cell cytoplasm. The spatial distribution of Na+ currents, produced by a local superfusion of the cell surface, indicates a nonuniform, patchy accumulation of apical Na+ transporters in the vicinity of the nucleus. Such pathways for direct Na+ flux between extracellular space and cell nucleus could be potentially important for gene activation. IMAGES:
提供机构：
National Academy of Sciences
创建时间：
1992-01-01
