Metabolomic Rewiring in Endocrine Therapy-Resistant Estrogen Receptor Positive Breast Cancer. Metabolomic Rewiring in Endocrine Therapy-Resistant Estrogen Receptor Positive Breast Cancer

We report mRNA profiles of human breast cancer cell lines, SUM159 and SUM149,which are modulated fatty acid beta oxidation (FAO) pathway either pharmacologically using Etomoxir (ETX) or genetically (shRNA). The optimized data analysis workflows reported here should provide a framework for comparative investigations of expression profiles. Overall design: mRNA profiles of human breast cancer cell lines after modifying fatty acid beta oxidation (FAO)