Analytes that differ in levels between cognitively normal (CDR 0) and very mildly/mildly demented (CDR 0.5 and 1) participants.

Analysis of covariance (ANCOVA) using the General Linear Model (GLM) procedure in SAS was used to determine analytes that differed in concentration (p0 groups while adjusting for the effects of age and gender ("adjusted means").*indicates analytes that were significant after Bonferroni correction based on the number of markers analyzed (128 markers, cutoff of 0.0004 for familywise p0 groups.