3-Nitro-3-deaza-2‘-deoxyadenosine as a Versatile Photocleavable 2‘-Deoxyadenosine Mimic
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A new photocleavable 2‘-deoxyadenosine mimic, 3-nitro-3-deaza-2‘-deoxyadenosine (NidA), was prepared and introduced into DNA fragments via its 6-O-trimethylphenyl precursor phophoramidite. Photocleavage of the resulting oligonucleotide is highly efficient in single and double strands. Hybridization properties of NidA are very similar to those of deoxyadenosine.
创建时间：
2004-08-11
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