Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with an (R)-methyl substitued Fasudil-derivative.

Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with an (R)-methyl substitued Fasudil-derivative. Descriptor: 5-[[(2~{R})-2-methyl-1,4-diazepan-4-ium-1-yl]sulfonyl]isoquinoline, METHANOL, cAMP-dependent protein kinase catalytic subunit alpha, ... Authors: Wienen-Schmidt, B, Heine, A, Klebe, G. Deposit date: 2016-10-26 Release date: 2018-06-06 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.488 Å) Cite: Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with differently methylated Fasudil-derived ligands To be Published

cAMP依赖性蛋白激酶（cAMP-dependent Protein Kinase, PKA）与一种(R)-甲基取代法舒地尔衍生物形成的共晶体结构。
描述符：5-[[(2R)-2-甲基-1,4-二氮杂环庚烷-4-鎓-1-基]磺酰基]异喹啉、甲醇、cAMP依赖性蛋白激酶催化亚基α等。
作者：Wienen-Schmidt, B、Heine, A、Klebe, G。
存入日期：2016-10-26，发布日期：2018-06-06，最后修改日期：2024-11-06。
实验方法：X射线衍射（分辨率1.488埃）。
引用说明：与不同甲基化法舒地尔衍生配体结合的cAMP依赖性蛋白激酶共晶体结构，待发表。