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Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble

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RNA聚合酶转录

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Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble

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2024-11-13

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RNA聚合酶转录

Despite the critical regulatory function of promoter-proximal pausing, the influence of pausing kinetics on transcriptional control remains an active area of investigation. Here, we present Start-Time

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Rora, Ep300, Ppargc1a bind Arntl (Bmal1) gene

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Rora binds the RRE DNA element and recruits the coactivators Pgc-1alpha (Ppargc1a) and p300 (Ep300, a histone acetyltransferase). Rora binds the promoter of the Arntl gene and enhances transcription.

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RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dUTP

RNA聚合酶II延伸复合物

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RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dUTP

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Additional file 5 of The spatial distribution of cis regulatory elements in yeast promoters and its implications for transcriptional regulation

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Additional file 5: A complete list of genes used in this study. This table includes the lists of genes of each group of TATA box-containing, TATA box-less, Type I-Type IV and the data of 5'UTR length,

DataCite Commons2024-02-15 更新90

PP1 PNUTS binds the “restrictor” and dephosphorylates pol II CTD Ser5 to stimulate RNA pol II transcription termination [eNET-seq]

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RNA聚合酶转录

The restrictor complex, WDR82/ZC3H4, is the major termination factor for antisense transcription from bidirectional promoters, but its mechanism of action is poorly understood. We report that the PP1

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Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble

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