Organocatalytic and Enantioselective Synthesis of β-(Hydroxyalkyl)-γ-Butyrolactones
收藏NIAID Data Ecosystem2026-03-06 收录
数据链接：
官方服务：
资源简介：
Organocatalytic cross-aldol reaction of methyl 4-oxobutyrate (2) and a variety of aldehydes 3 followed by reduction with NaBH4 has provided a one-pot, general and efficient method for the synthesis of 4-(hydroxyalkyl)-γ-butyrolactones 1 with high diastereo- (dr > 24:1) and enantioselectivity (ee > 99%).
创建时间：
2008-05-16
