Gene-gene interactions affect oesophageal cancer risk.

NOTE: Individuals with multi-locus genotype of interest are compared against the rest of the individuals, which are considered as a reference group in each logistic regression analysis. Low Risk, deceased risk for malignancy; High Risk, increased risk for malignancy.aNumber of SNPs considered. Genotypes with most significant effects for each interaction (i.e. lowest P-value) are printed in bold. Statistical significance for each interaction was further determined by 1000 permutations test (P1000).