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A crispr-cas9 screen was performed to search for new target genes for MTMCT.
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创建时间：
2025-04-28
相关数据集
A Type II-B Cas9 nuclease with no detectable off-targets and reduced chromosomal translocations in vivo.
Streptococcus pyogenes Cas9 (SpCas9) and derived enzymes are widely used as components of CRISPR-Cas9 genome editing and engineering platforms. However, they exhibit promiscuous nuclease activity that
NIAID Data Ecosystem60
Additional file 5 of DNA polymerases in precise and predictable CRISPR/Cas9-mediated chromosomal rearrangements
Additional file 5: Table S3. Supporting data values.
Figshare2024-08-16 更新40
SuperFi Cas9 - 20nt sgRNA - DNA ternary complex Class E
SuperFi Cas9 - 20nt sgRNA - DNA ternary complex Class E Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (50-MER), RNA (102-MER) Authors: Zheng, R, Ma, L.J. Deposit date: 2025-08-12 Release d
Protein Data Bank Japan2026-05-06 更新20
CRISPR-Cas9 knockout screens using the miRNA-targeting lentiG-miR library
The data includes NGS data analyses from CRISPR-Cas9 knockout screens for 47 human cancer cell lines, performed with PoolQ (v2.2.0). This output includes raw read counts of sgRNAs and corresponding qu
Figshare2024-04-25 更新40
The safety of highly stable Cas9 in mice
Twenty-four male C57BL/6 mice (5 weeks old) were randomly divided into three groups (NC, Cas9, and HSCas9 groups). NC group were hydrodynamically injected with the plasmid pBB4.5-1.3HBV, PX458-Cas9, a
NIAID Data Ecosystem30
