Additional file 5: Table S4. of Cribriform and intraductal prostate cancer are associated with increased genomic instability and distinct genomic alterations
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Gene-wise copy number alterations detected in the TCGA cohort and validated in the CPC-GENE cohort using a ≥ 30% CR/IDC threshold to stratify samples. Columns contain: Symbol – official gene symbol, Chromosome / Start / End – genomic coordinates of gene locus, FDR – Boschloo’s exact test p-value after correcting for multiple tests using the Benjamini–Hochberg procedure for specified dataset. amplifications_case – number of CR/IDC positive samples in specified dataset with an amplification spanning gene locus, amplifications_control – number of control samples in specified dataset with an amplification spanning gene locus, cases – total number of CR/IDC positive samples in specified dataset, controls – total number of control samples in specified dataset. All entries are sorted by genomic location. Deletions are presented in the same format and listed separately. (PDF 12328 kb)



