Estimated in vivo % residual human mitochondrial polymerase- activity in resting cells.
收藏Figshare2015-12-02 更新2026-04-29 收录
下载链接：
https://figshare.com/articles/dataset/_Estimated_in_vivo_residual_human_mitochondrial_polymerase_activity_in_resting_cells_/361917
下载链接
链接失效反馈官方服务：
资源简介：
In vivo concentration ranges were 3TC-TP = 12.2–40.5; FTC-TP = 1.5–19.4; TFV-DP = 0.16–1.17; CBV-TP = 0.44–0.88; d4T-TP = 0.034–0.56; and AZT-TP = 0.0056–0.056 , respectively [56], [71], [73]–[75], assuming an average cell volume of for resting T-cells [72].*calculated as the ratio of average effect on polymerase- and wildtype reverse transcriptase of HIV-1: .†mitochondrial toxicity of AZT has been attributed to mechanisms other than inhibition (see Discussion section).
创建时间：
2015-12-02
