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Microarray analysis of white adipose tissue and liver from CD301b+ MNP-depleted mice

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE84809
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Tissue-resident mononuclear phagocytes (MNPs) in metabolic organs contribute to the regulation of whole body metabolism. CD301b+ MNPs are a subset of MNPs that are found in most peripheral organs including metabolic organs. In a mouse model in which CD301b+ MNPs can be selectively and transiently depleted, we examined the impact of the depletion on gene expression in the white adipose tissue and the liver. Male Mgl2-DTR mice or control wild-type mice were treated with diphtheria toxin for 10 days to depleted CD301b+ MNPs. Total RNA was isolated frrom the inguinal and epididymal white adipose tissue and the liver.
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2018-02-21
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