Feeding with a ketonic diet confers complete protection against malaria

The administration of a ketogenic diet (KD) to mice conferred 100% protection against Plasmodium berghei infection. The mechanisms underlying KD-mediated Plasmodium parasite development inhibition from the perspective of gene expression regulation was investigated. A genome-wide transcriptomic analysis was performed with PbA iRBCs from KD-fed and RD-fed mice.