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The effect of growth rate on pyrazinamide activity in Mycobacterium tuberculosis; insights for early bactericidal activity

ChEBI2016-03-25 更新2026-07-12 收录

结核病药物机制

细菌生长速率与药效

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-4093 数据链接链接失效反馈

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The effect of growth rate on pyrazinamide activity in Mycobacterium tuberculosis; insights for early bactericidal activity

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创建时间：

2016-03-25

结核病药物机制

细菌sRNA表达分析

M. tuberculosis grown at an MGT of either 23.1h (fast growth) or 69.3h (slow growth) was exposed to an MIC level (0.5 mg L-1) of isoniazid. LIMMA analysis was used to identify differentially expressed

NIAID Data Ecosystem50

Transcriptional Response of Mycobacterium tuberculosis H37Rv to Delamanid. Transcriptional Response of Mycobacterium tuberculosis H37Rv to Delamanid

结核分枝杆菌转录

结核病药物机制

To understand the response of M. tuberculosis (MTB) to the drug delamanid, we performed transcriptomics on MTB bacilli exposed to the drug. Overall design: Bacteria were harvested at 0,1 day after bei

NIAID Data Ecosystem40

Crystal structure of the S324T variant of Burkholderia pseudomallei KatG with isonicotinic acid hydrazide bound

蛋白质晶体学

结核病药物机制

Crystal structure of the S324T variant of Burkholderia pseudomallei KatG with isonicotinic acid hydrazide bound Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Catalase-peroxidase, ... Author

Protein Data Bank Japan2024-10-23 更新30

Mycobacterium tuberculosis transcriptional response to Pyrazinoic acid. Mycobacterium tuberculosis transcriptional response to Pyrazinoic acid

结核病药物机制

细菌转录组学

The ability of Mycobacterium tuberculosis (Mtb) to adopt heterogeneous physiological states, underlies it’s success in evading the immune system and tolerating antibiotic killing. Drug tolerant phenot

NIAID Data Ecosystem50

Transcriptional Responses of M. tuberculosis to inhibitors of metabolism. Mycobacterium tuberculosis H37Rv

结核分枝杆菌药物转录组

结核病药物机制

Transcriptional profiling of M.tuberculosis was performed using 430 whole-genome microarrays to measure the effects of 75 different drugs, drug combinations or different growth conditions at various t

NIAID Data Ecosystem40

The effect of growth rate on pyrazinamide activity in Mycobacterium tuberculosis; insights for early bactericidal activity

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