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Summary of activity of compounds in inhibiting Stat3 binding to pY peptide ligand in a surface plasmon resonance binding (SPR) assay, in inhibiting IL-6-mediated Stat3 phosphorylation (pStat3) and in inhibiting IL-6-mediated Stat3 nuclear translocation in a high-throughput fluorescence microscopy (

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1Data presented are IC50 values (µM) obtained using results summarized in Figures 1 (SPR), Figure 2 (pStat3) and Figure 4 (HTFM).

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2013-02-21
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