The method and composition for improving the efficiency of the target gene modification which uses oligonucleotide mediation type
收藏国家林业和草原科学数据中心2023-02-12 更新2024-03-07 收录
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Provided herein include methods and compositions for making targeted changes to a DNA sequence. In various aspects and embodiments， methods and compositions for modifying a DNA sequence in a cell (such as a plant， bacterial， yeast， fungal， algal， or mammalian cell) are provided. In some aspects and embodiments the modification of DNA involves combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms， such as a DNA cutter. Provided herein include methods and compositions for making targeted changes to a DNA sequence. In various aspects and embodiments， methods and compositions for modifying a DNA sequence in a cell (such as a plant， bacterial， yeast， fungal， algal， or mammalian cell) are provided. In some aspects and embodiments the modification of DNA involves combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms， such as a DNA cutter.
提供机构：
国家林业和草原科学数据中心
创建时间：
2023-02-12
