The efficacy and safety of perioperative chemotherapy for locally advanced colorectal cancer. - The phase II study-
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Interventions: 1) All RAS wild-type: 6 courses of cetuximab+mFOLFOX6 or 4 courses of cetuximab+SOX is performed, followed by curative operarion. 2) All RAS mutant-type: 6 courses of FOLFOXIRI or SOXIRI is performed, followed by curative operation. Primary outcome(s): Response rate (judged by enhanced CT and MRI on 12 weeks after initiation of chemotherapy) Study Design: Single arm Non-randomized
创建时间:
2016-09-15



