Estimated rates of total NAD synthesis (“amidated” plus “deamidated”) in mouse tissues.

aSum of estimated rates of “amidated” (Table 2) and deamidated routes (Table 3).bValues are calculated by the equation (4) shown in Methods, using the in vivo total NAD synthesis rate as “v” value (assumed to equal the in vivo total NAD degradation rate), and the NAD level in each tissue (Figure 4).Estimated rates of total NAD synthesis (“amidated” plus “deamidated”) in mouse tissues.