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Glucocorticoids Promote Breast Cancer Metastasis

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NIAID Data Ecosystem2026-03-11 收录
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Next Generation Sequencing was applied to investigate the heterogeneity between tumors and distant metastases in different models of Breast Cancer cell lines and primary-derived xenografts. Global transcriptional profiling of the primary tumor and matched distant metastases (lung, liver, spleen) as well as circulating tumor cells (CTCs) allowed to identify glucocorticoid signalling as a mediator of metastasis. RNA-Seq in 4 different Breast Cancer models to investigate glucorticoid signalling role in metastasis

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2019-03-27
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