Crystal structure of LSD1-CoREST in complex with PRSFLVRRP peptide

Crystal structure of LSD1-CoREST in complex with PRSFLVRRP peptide Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ... Authors: Kikuchi, M, Kitagawa, H, Sato, S, Umezawa, N, Higuchi, T, Umehara, T. Deposit date: 2020-06-19 Release date: 2021-06-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.64 Å) Cite: Structure-Based Identification of Potent Lysine-Specific Demethylase 1 Inhibitor Peptides and Temporary Cyclization to Enhance Proteolytic Stability and Cell Growth-Inhibitory Activity. J.Med.Chem., 64, 2021与PRSFLVRRP肽结合的LSD1-CoREST晶体结构 描述符：黄素腺嘌呤二核苷酸（FLAVIN-ADENINE DINUCLEOTIDE）、甘油（GLYCEROL）、赖氨酸特异性组蛋白去甲基化酶1A（Lysine-specific histone demethylase 1A）…… 作者：Kikuchi M、Kitagawa H、Sato S、Umezawa N、Higuchi T、Umehara T 提交日期：2020-06-19 发布日期：2021-06-23 最后修改日期：2023-11-29 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.64 Å 引用文献：《基于结构识别强效赖氨酸特异性去甲基化酶1抑制肽及临时环化以增强蛋白水解稳定性与细胞生长抑制活性》，J.Med.Chem., 64, 2021