Sutural fibroblasts exhibit the function of vascular endothelial cell upon mechanical strain

Midfacial hypoplasia is a kind of facial dysplasia. The technique of trans-sutural distraction osteogenesis(TSDO) can promote midface growth so as to ameliorate this symptom. Here, we used single-cell RNA sequencing to define the rat's cell classification of zygomatic maxillary suture and the changes of cell clusters in the suture before and after seven-day distraction. Overall design: one sample is from the 7-day-distracted zygomatic maxillary suture (experimental group, distraction osteogenesis group, DO), another sample is from the sham operation zygomatic maxillary suture (controlled group, sham operation controlled group, SC)