Palladium-Catalyzed Synthesis of 2,3,4-Trisubstituted Furans via Cascade Reactions of Aryloxy-enynes with Aryl Halides

A highly efficient palladium-catalyzed cascade reactions
of aryloxy-enynes
with aryl halides under mild reaction conditions has been developed.
This methodology offers rapid access to 2,3,4-trisubstituted furans
in good to excellent yields in a regioselective manner.

一种在温和反应条件下，以高效钯催化实现的芳氧烯炔与芳基卤化物的级联反应已被开发。该方法能够快速以良好的至优异的产率，以区域选择性的方式获得2,3,4-三取代呋喃。