Crystal structure of 6-fluoropyrazolo[1,5-a]pyridine derivative bound to KIT
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Crystal structure of 6-fluoropyrazolo[1,5-a]pyridine derivative bound to KIT Descriptor: Mast/stem cell growth factor receptor Kit, ~{N}-[5-(5-cyclopropyl-4~{H}-1,2,4-triazol-3-yl)-4-fluoranyl-2-methyl-phenyl]-6-fluoranyl-pyrazolo[1,5-a]pyridine-3-carboxamide Authors: Walker, N.P, Jeffrey, J.L, Blaesse, M. Deposit date: 2026-04-02 Release date: 2026-08-05 Last modified: 2026-08-26 Method: X-RAY DIFFRACTION (2.629 Å) Cite: Discovery of a Potent, Orally Bioavailable Small-Molecule Inhibitor of Wildtype KIT with Exceptionally High Kinome Selectivity. J.Med.Chem., 69, 2026
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2026-04-02
