Monocytes are integral cells of the innate immune system that play important roles in host defence and tissue repair. It is well established that monocytes are derived from the common monocyte progeni

NIAID Data Ecosystem10

Human Deoxyhypusine Synthase Fragment Screening Campaign - UNLand VT00188

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脱氧羟腐胺赖氨酸合酶

Human Deoxyhypusine Synthase Fragment Screening Campaign - UNLand VT00188 Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 4-(trifluoromethyl)-3~{H}-pyridin-6-one, Deoxyhypusine synthase, ... Authors: Wilk,

Protein Data Bank Japan2026-02-18 更新10

Phenotyping of macrophages derived from TpMos and Mature Ly6Chi monocytes

单核细胞亚群分化

巨噬细胞炎症表型

NIAID Data Ecosystem40

IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation. IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation

单细胞转录组学

巨噬细胞炎症表型

We explored how the human macrophages response to different inflammatory factors, focusing particularly on the effects of antiviral interferons (IFN-β and IFN-γ), pro-inflammatory cytokines such as TN

NIAID Data Ecosystem10

Deoxyhypusine Synthase promotes a pro inflammatory macrophage phenotype

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