Figure 3_plot binding curves

BMK-DKO cells expressing CBcl-2, transfected with VBH3 proteins and treated with BH3 mimetics. This folder contains each binding curve plotted in STEP 10 of qF3 analysis. Filename includes information: "Well ID_Donor Fusion Protein_Transfectant_Treatment_Treatment concentration". Where a decimal in concentration is replaced with a dash in the filename. ie. 1.25uM is 1-25uM. The Filename of the file corresponds to the data plotted in Red. Positive and Negative controls (VBH3 and VBH3-4E) are plotted on each graph for comparison in Blue and Grey, respectively. If the data could be fit, then fit is displayed on the graph. Data displayed in Figure 3 was generated from combining results of 4 screens: 1) BclXL_Bcl2_screen {Rep1_20180822, Rep2_20180823, Rep3_20180830, Rep4_20180831} 2) mim2_Bcl2_screen {Rep1_20190326, Rep2_20190327, Rep3_20190328, Rep4_20190329} 3) XL2W_screen {Rep1_20191108, Rep2_20191109, Rep3_20191110, Rep4_20191111} 4) PumaV_screen {Rep1_20200909, Rep2_20200910, Rep3_20200916, Rep4_20200917} - see, "Figure 3" Dataset in dataverse for associated .CSV files for each binding curve.