Analysis of Circulating Extracellular Vesicle microRNAs in Breast Cancer Patients with Obesity: a Potential Role for Let-7a. Analysis of Circulating Extracellular Vesicle microRNAs in Breast Cancer Patients with Obesity: a Potential Role for Let-7a

To study the impact of the obesity condition on circulating Extracellular Vesicle-miRNA expression signature in breast cancer patients, and identify potential obesity-related miRNAs that may be associated with progression. Overall design: Comparative EV-miRNA expression profiling analysis of RNA-seq data for circulating EVs in breast cancer patients categorized based on their Body Mass Index in Normal weight (NW; 18 > BMI 25 Kg/m2).