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Supplementary File S3 from Integrated human-virus metabolic stoichiometric modelling predicts host-based antiviral targets against Chikungunya, Dengue and Zika viruses.

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Results for the reaction knockout and host-derived enforcement analyses. Model reactions and model subsystems are listed. The resulting virus optima, for CHIKV, DENV and ZIKV, are shown as a percentage of the original model (without the additional constraints imposed by the analyses). The lower and upper flux bounds used for the host-derived enforcement analysis are listed for the relevant reaction and associated virus optimisation result.

提供机构:
The Royal Society
创建时间:
2020-10-15
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