RNAseq of control and Sting-/- L929 cells to compare gene expression change RNA was extracted from control and Sting-/- L929 cells and RNA-seq was performed. Three replicates are included for each sam

NIAID Data Ecosystem00

Gene expression in STING-/- MEF cells expressing STING R284S variant. Gene expression in STING-/- MEF cells expressing STING R284S variant

STING R284S variant is constitutively active and induces inflammatory genes even in absence of STING ligand cGAMP. Overall design: Wild-type STING, N154S (SAVI mutant) and R284S were expressed in STIN

NIAID Data Ecosystem50

The effect of myeloid STING knockout on gene expression in colitic mice. The effect of myeloid STING knockout on gene expression in colitic mice

Myeloid-derived STING has been recognized to play a vital role in mediating the development of colitis. We here report that myeloid-specific knockout of STING in adult mice ameliorates DSS-induced acu

NIAID Data Ecosystem00

STING affects gene expression. STING affects gene expression