NaCl and urea modulate antiviral CD8+ T cell survival, renal accumulation and response to BKV

Primary human PBMC were treated with allogenic stimulation and elevated NaCl or Urea concentrations. RNA from sorted CD8 Tcells was analyzed for differential expression in high osmolyte environments. Overall design: Primary human PBMC were treated with allogenic stimulation and elevated NaCl or Urea concentrations. RNA from sorted CD8 Tcells was analyzed for differential expression in high osmolyte environments.