pan-genome of cultivated and wild sorghum

Sorghum is a drought tolerant staple crop for half a billion people in Africa and Asia, an important source of animal feed throughout the world and a biofuel feedstock of growing importance. Cultivated sorghum and its inter-fertile wild relatives constitute the primary gene pool for sorghum. Understanding and characterising the diversity in the primary gene-pool is fundamental for its effective utilisation in crop improvement activities. Here, we report the first sorghum pan-genome comprising cultivated sorghums and its wild relatives to explore the diversity within the sorghum primary gene pool. With 13 genomes de novo assembled using a combination of short-read and long-read sequencing, we have generated a pan-genome of 51,349 gene families (35% of which are core genes), and identified 185.29 Mb sequence absent from the reference genome.

搜集汇总

背景与挑战

背景概述

该数据集是首个栽培和野生高粱的泛基因组，基于13个基因组的从头组装，揭示了51,349个基因家族（其中35%为核心基因），并鉴定出参考基因组中缺失的185.29 Mb序列，为高粱遗传多样性研究和作物改良提供了重要资源。