Associations between extended class I-HLA-LTA-TNF-LST1 haplotypes and class I HLA-only haplotypes, and rubella-specific cytokine responses.

Only haplotypes with estimated frequencies ≥0.01 and p-values ≤0.15 are presented.aHaplotype effects estimated using a haplotype t-statistic that assesses associations of cytokine levels across haplotypes. Allele p-value compares the haplotype of interest to all other haplotypes combined. Statistically significant findings (pbCommon SNPs from the LTA gene: [rs2857602 (A>G), rs2857708 (G>A), rs915654 (T>A), rs2844482 (G>A), rs1041981 (C>A), rs1799964 (A>G), rs1799724 (G>A)]; TNF gene: rs1800629 (G>A); LST1 gene: [rs2256965 (G>A), and rs2256974 (C>A)].