RNA-seq of LPS-primed TGR5+/+ BMDCs and TGR5-/- BMDCs treated with LCA
收藏NIAID Data Ecosystem2026-03-12 收录
官方服务：
资源简介：
To investigate the underlying mechanism on TGR5 signaling inhibiting DCs activation.
应用场景：
创建时间：
2021-09-06
相关数据集
PTBP1 is necessary for dendritic cells to regulate T cells homeostasis and antitumor immunity. PTBP1 is necessary for dendritic cells to regulate T cells homeostasis and antitumor immunity
Dendritic cells (DCs) play an important role in innate and adaptive immunity. DCs could sense environment pathogens and tumors, presenting those antigens to T cells. PTBP1, an RNA-binding protein, the
NIAID Data Ecosystem100
RNA-Seq analysis of recombinant articulatin B chain treated murine bone marrow-derived dendritic cells. RNA-Seq analysis of recombinant articulatin B chain treated murine bone marrow-derived dendritic cells
We performed RNA-seq analysis using primary murine bone marrow derived dendritic cells (BM-DCs) for recombinant articulatin B chain (rATB) treatment. We reported that rATB regulates immunological rela
NIAID Data Ecosystem80
The clonal and molecular aetiology of Flt3L-mediated 'emergency' dendritic cell development
Flt3 ligand (Flt3L) promotes an increased generation of type 1 conventional dendritic cells (cDC1s), resulting in enhanced immunity against infections and cancer. Here, we employ cellular barcoding to
NIAID Data Ecosystem80
SMRT controlled inflammation in cDC1 is orchestrated through mTOR-Succinate axis despite of suppressed glycolysis. SMRT controlled inflammation in cDC1 is orchestrated through mTOR-Succinate axis despite of suppressed glycolysis
Immunogenic activation of DCs by TLRs involves coordinated metabolic and transcriptional rewiring. The negative regulation of such metabolic rearrangements in DCs remains elusive. We have recently rep
NIAID Data Ecosystem100
Expression of canonical transcription factor-target TLR4-dependent pathways mediating the LPS response in CD8 and CD11b DCs.
Transcription factor-target over-representation analysis of LPS-induced genes in CD8 and CD11b DCs. 1. The ratio of odds (Odds-Ratio) that a transcription factor-associated pathway is enriched in the
NIAID Data Ecosystem80
