Study Descriptions.

Abbreviations: European American (EA), African American (AA), Hispanic/Mexican American (H), Asian/Pacific Islander (API).
1Data from PAGE studies available for this PheWAS include: Atherosclerosis Risk in Communities (ARIC), Cardiovascular Health Study (CHS), Epidemiologic Architecture for Genes Linked to Environment (EAGLE), Multiethnic Cohort (MEC), and Women's Health Initiative (WHI). PAGE study sites and study design descriptions are in Text S1.
2Pubmed ID of study description manuscript for each study.
3Maximum sample size and Minimum sample size are dependent both on who was genotyped and who had a specific phenotype measured. Not all phenotypic measurements were available for all participants within each study.
4This is the total number of SNPs available for each study. Table S1 has the list of these SNPs for each study, genotyped across two or more studies.
5This includes the number of phenotypes transformed and untransformed, as well as categorical phenotypes divided into binary phenotypes, full description in Materials and Methods.
6Total number of tests of association calculated for each study, in parenthesis is the total number of associations with p<0.01.