Quantifying second messenger information transmission in bacteria.

Jin_SourceData_Fig1.xlsx provides raw data for the dose-response curve of the cAMP sensor and the temporal changes in fluorescence intensity under light and dark conditions. Jin_SourceData_Fig2.xlsx contains the raw data of two key parameters (k and γ) extracted from individual bacterial cells across all experiments, along with the original measurements of cAMP signal intensity and signal-to-noise ratio as a function of reduced frequency. These experimental measurements serve as the foundation for the theoretical analysis and computational modeling presented in Figure 3. Jin_SourceData_Fig4.xlsx contains raw data of intracellular cAMP dynamics in single bacterial cells under random light stimulation with various code durations, and the relationship between decoding accuracy and frequency presented in the main text.