Pharmacokinetics and toxicity profiles of ten selected compounds.

Figshare2025-06-10 更新2026-04-28 收录

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资源简介：

Pharmacokinetics and toxicity profiles of ten selected compounds.

创建时间：

2025-06-10

碘佛醇结构的小分子渗透性预测评价数据

造影剂渗透性预测

药物ADMET

造影剂因分子量大（通常500～1500 g/mol）、极性表面积高（TPSA普遍超过140 Å²），整体理化性质远超传统Lipinski五规则适用范围，通用ADMET预测工具对此类分子的渗透性预测精度严重不足。细胞膜渗透性是限制造影剂口服吸收及组织分布的关键瓶颈，然而现有公开Caco-2渗透性数据库对造影剂母核结构及其药典法定杂质的覆盖极为有限，导致研发团队在早期筛选阶段只能依赖耗时耗力的体外Ca

浙江省数据知识产权登记平台2026-05-07 更新100

ADMET properties of chemical compounds present in Senna in comparison with the active phytochemicals and FDA-approved drugs.

药物ADMET

天然产物药物化学

ADMET properties of chemical compounds present in Senna in comparison with the active phytochemicals and FDA-approved drugs.

Figshare2022-06-14 更新40

ADMET Profile of Selected DHPS Virtual Screening Hits and Analogues.

药物ADMET

虚拟筛选化合物库

ADMET Profile of Selected DHPS Virtual Screening Hits and Analogues.

Figshare2026-03-20 更新10

MOESM6 of IDAAPM: integrated database of ADMET and adverse effects of predictive modeling based on FDA approved drug data

药物ADMET

不良反应预测

Additional file 6. SQL script to store FAERS adverse effect from CSV file to IDAAPM.

DataCite Commons2024-12-17 更新60

Adsorption, distribution, metabolism, toxicity properties and predicted pIC 50 of Saracatinib and the top three TCM compounds.

药物ADMET

化合物筛选

*Control. 1ADMET Adsorption levels: 0 = Good; 1 = Moderate; 2 = Low; 3 = Very low. 2Plasma Protein Binding: 0 = Binding 90%; 2 = Binding >95%. 3Inhibition probability of Cytochrome

NIAID Data Ecosystem10

Pharmacokinetics and toxicity profiles of ten selected compounds.

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