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Efficient Construction of Cyclopenta[<i>b</i>]quinoline Core of Isoschizozygane Alkaloids via Intramolecular Formal Hetero-Diels−Alder Reaction

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NIAID Data Ecosystem2026-03-06 收录
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Acid-catalyzed condensation of aromatic amines with δ,ε-unsaturated aldehydes, followed by intramolecular formal hetero Diels−Alder reaction, is described as a potential route to the cyclopenta[b]quinoline substructure of isoschizozygane alkaloids. Reactions are highly diastereoselective and produce adducts with up to four contiguous stereocenters.

创建时间:
2016-08-20
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