Synthesis of Functionalized Indolizidines through Pauson–Khand Cycloaddition of 2‑Allylpyrrolidines
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A concise entry to functionalized indolizidine scaffolds through a domino 2-aza-Cope-[3 + 2] dipolar cycloaddition and Pauson–Khand [2 + 2 + 1] cyclization has been accomplished. The process was conducted under mild conditions to afford diverse indolizidine systems as single diastereomers in good overall yields.
创建时间:
2016-02-20



