GutierrezBarragan_CB2021_halothane_rsfMRI_mouse_part2
收藏资源简介:
Resting state fMRI data from n=9/19 mice under medetomidine-isoflurane anesthesia (mice were first deeply anesthetized with isoflurane 4% induction, intubated and artificial ventilated 90 BPM, then switched to halothane 0.75%) from Gutierrez-Barragan et al. 2021 (DOI pending). Scans were acquired at the IIT laboratory in Rovereto (Italy) on a 7.0 Tesla MRI scanner (Bruker Biospin, Ettlingen) with a BGA-9 gradient set, a 72 mm birdcage transmit coil, and a four-channel solenoid receive coil. Awake scans used a single-shot echo planar imaging (EPI) sequence with the following parameters: TR/TE=1200/15 ms, flip angle=60°, matrix=100 x 100, 24 coronal slices (voxel-size 200 x 200 x 500 µm), for a total of 1600 time points, total acquisition time of 32 minutes. It is suggested to remove the first 100 scans (2 minutes) to account for thermal gradient equilibration.
本数据集包含来自Gutierrez-Barragan等人2021年研究(DOI待提交)的、处于美托咪啶-异氟烷麻醉状态下的9/19只小鼠的静息态功能磁共振成像(functional magnetic resonance imaging,fMRI)数据。麻醉实施流程为:首先以4%异氟烷诱导小鼠深度麻醉,随后进行气管插管并施以90次/分钟的人工通气,最后切换为0.75%浓度的氟烷维持麻醉。扫描数据采集于意大利罗韦雷托的IIT实验室,使用设备为7.0特斯拉磁共振成像扫描仪(Bruker Biospin公司,埃特林根),配套BGA-9梯度线圈组、72毫米鸟笼式发射线圈以及四通道螺线管接收线圈。清醒状态下的扫描采用单次回波平面成像(echo planar imaging,EPI)序列,具体参数如下:重复时间/回波时间(TR/TE)=1200/15毫秒,翻转角=60°,矩阵尺寸=100×100,共24层冠状位切片,体素大小为200×200×500微米,总采集时长32分钟,共包含1600个时间点。建议移除前100帧扫描数据(对应时长2分钟)以校正热梯度平衡效应。




