ATRA: C. elegans Swim Test (CeleST)

The Caenorhabditis Intervention Testing Program (CITP) is a multi-institutional program that seeks robust and reproducible pro-longevity interventions that are efficacious across genetically diverse cohorts in the Caenorhabditis genus. The project features a unique design in which multiple experimental replicates are collected by three different laboratories at discrete locations for all candidate compounds tested. To limit confounding factors that may influence experimental reproducibility, we develop standardized operating procedures (SOPs) for all experimental procedures. Here we provide the data, R scripts, and analysis used in the CITP manuscript: Survey of anti-aging computational predictions identifies all-trans retinoic acid modulation of conserved longevity pathways in genetically diverse Caenorhabditis nematodes