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DSCR1 upregulation enhances dural meningeal lymphatic drainage to attenuate amyloid pathology of Alzheimer's disease

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NIAID Data Ecosystem2026-03-13 收录
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Purpose: To further understand the beneficial effects of DSCR1 on the lymphatic system of 5XFAD mice, we investigated the transcriptional landscape of meningeal lymphatic endothelial cells (mLECs) by performing RNA sequencing. Overall design: mRNA profiles of meningeal lymphatic endothelial cells (mLECs) were isolated from 3-4 mice of each strain using MACS, in quadruplicate

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2021-11-16
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