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Enantioselective Construction of Spiroindolenines by Ir-Catalyzed Allylic Alkylation Reactions

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https://figshare.com/articles/dataset/Enantioselective_Construction_of_Spiroindolenines_by_Ir_Catalyzed_Allylic_Alkylation_Reactions/2739430
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资源简介:
With 2-methyl-1,2,3,4-tetrahydroquinoline-derived phosphoramidite ligand (R,Ra)-L6, Ir-catalyzed intramolecular C-3 allylic alkylation of indoles has been realized to afford highly enantioenriched spiroindolenine derivatives in 92−98% yields with up to >99/1 dr and 97% ee.
创建时间:
2010-08-25
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