Supplementary Data for "Time to Benefit of Surgery vs. Targeted Medical Therapy for Patients with Primary Aldosteronism: A Meta-analysis"

Supplemental Methods. Additional details regarding methods.

Table S1. Electronic search strategies.

Table S2. Risk of bias of included studies.

Table S3. Time-to-benefit for prevention of all-cause mortality following surgery compared to medical therapy.

Table S4. Sensitivity analysis for uncontrolled confounding.

Figure S1. Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) flow diagram.

Figure S2. Stratified analyses according to subtype of primary aldosteronism.

Figure S3. Meta-analyses of selected adverse outcomes.

Figure S4. Contour-enhanced funnel plots and Egger’s linear regression test.

Supplemental References.